MRP2抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
MRP2抗体

MRP2抗体

商家询价

产品名称： MRP2抗体

英文名称： MRP2Antibody

产品编号： XY24893-1-

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 MRP2抗体

Applications
Tested Applications: ELISA, IHC, WB
Specificity Reaction: Human, Mouse; Other species are not tested.Please decide the specificity by homology
Positive WB detected in HepG2 cells, mouse kidney tissue
Positive IHC detected in Human small intestine tissue
Recommended dilution WB : 1:200-1:2000
IHC : 1:20-1:200
 MRP2抗体Application key: WB=Western Blotting ,IHC=Immunohistochemistry, IF=Immunofluorescence
Images
Prev1NextView more validation data
  • 24893-1-AP;HepG2 cellsHepG2 cells were subjected to SDS PAGE followed by western blot with 24893-1-AP( ABCC2 Antibody) at dilution of 1:600
  • 24893-1-AP;human small intestine tissueImmunohistochemistry of paraffin-embedded human small intestine tissue slide using 24893-1-AP( ABCC2 Antibody) at dilution of 1:50 (under 10x lens)
  • 24893-1-AP;human small intestine tissueImmunohistochemistry of paraffin-embedded human small intestine tissue slide using 24893-1-AP( ABCC2 Antibody) at dilution of 1:50 (under 40x lens)
Product Information MRP2抗体
Source: Rabbit Purify: Antigen affinity purification
IsoType: IgG Storage: PBS with 0.1% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles.
Immunogen Information
Immunogen: MRP2 fusion protein ag18694 Full Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 2
Caculated Molecular
Weight:		 1545aa,174 kDa Observed Molecular 
Weight:		 190-250 kDa
GenbankNo BC136419 GeneID: 1244
Symbol ABCC2 Synonyms ABC30, ABCC2, MRP2
Background

Multi-drug resistance protein 2 (MRP2), also known as ABCC2, is an ATP binding cassette (ABC) transporter responsible for biliary excretion of xenobiotics, endobiotics, and their metabolites. Deficiency in ABCC2 results in the clinical disorder Dubin-Johnson syndrome. MRP2 is found to be expressed in a variety of human cancers, and is associated with resistance of tumor cells to various anticancer drugs including cisplatin. The predicted molecular weight of MRP2 is 174 kDa, while mature MRP2 usually has a slower migration around 190-250 kDa due to the glycosylation. (16434545, 18834541, 23045960) MRP2抗体

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