MAPK14 polyclonal antibody
产品名称： MAPK14 polyclonal antibody
英文名称： MAPK14 polyclonal antibody
产品编号： PAB18278
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of MAPK14.
- Immunogen:
- A synthetic peptide corresponding to residues surrounding Y322 of human MAPK14.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Specificity:
- This antibody is specific to MAPK14.
- Form:
- Liquid
- Purification:
- Affinity purification
- Concentration:
- 1 mg/mL
- Storage Buffer:
- In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:100)
Immunofluorescence (1:500-1:1000)
ELISA (1:5000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- J Biol Chem. 2005 Dec 30;280(52):43000-9. Epub 2005 Oct 24.
Khalil N, Xu YD, O'Connor R, Duronio V.J Biol Chem. 2005 Dec 30;280(52):43000-9. Epub 2005 Oct 24.
- 2.
- Am J Physiol Renal Physiol. 2002 Oct;283(4):F678-88.
Feifel E, Obexer P, Andratsch M, Euler S, Taylor L, Tang A, Wei Y, Schramek H, Curthoys NP, Gstraunthaler G.Am J Physiol Renal Physiol. 2002 Oct;283(4):F678-88.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of extracts from 293 cells, using MAPK14 polyclonal antibody (Cat # PAB18278).
Peptide "+" means "peptide blocking".
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Immunohistochemical analysis of paraffin-embedded human brain tissue using MAPK14 polyclonal antibody (Cat # PAB18278).
Peptide "+" means "peptide blocking".
- Entrez GeneID:
- 1432
- Protein Accession#:
- Q16539
- Gene Name:
- MAPK14
- Gene Alias:
- CSBP1,CSBP2,CSPB1,EXIP,Mxi2,PRKM14,PRKM15,RK,SAPK2A,p38,p38ALPHA
- Gene Description:
- mitogen-activated protein kinase 14
- Omim ID:
- 600289
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq
- Other Designations:
- Csaids binding protein,MAP kinase Mxi2,MAX-interacting protein 2,cytokine suppressive anti-inflammatory drug binding protein,p38 MAP kinase,p38 mitogen activated protein kinase,p38alpha Exip,stress-activated protein kinase 2A
- Interactome
- Gene Pathway
- Amyotrophic lateral sclerosis (ALS)
- Epithelial cell signaling in Helicobacter pylori infection
- Fc epsilon RI signaling pathway
- GnRH signaling pathway
- Leukocyte transendothelial migration
- MAPK signaling pathway
- Neurotrophin signaling pathway
- T cell receptor signaling pathway
- Toll-like receptor signaling pathway
- VEGF signaling pathway
- Related Disease