SIRT1 FRET-Based Screening Assay Kit
产品名称: SIRT1 FRET-Based Screening Assay Kit
英文名称: SIRT1 FRET-Based Screening Assay Kit
产品编号: KA1367
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
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- Specification
- Product Description:
- SIRT1 FRET-based Screening Assay Kit provides a fluorescence-based method for screening SIRT1 inhibitors or activators.
- Storage Instruction:
- Store the kit at -80°C.
- Note:
- Result Data
-
Inhibition of SIRT1 by Sirtinol (IC50= 38 uM).
- Protocol:
- Protocol Download
- MSDS:
- Download
- Regulation Status:
- For research use only (RUO)
- Application Image
- Functional Study
- Entrez GeneID:
- 23411
- Gene Name:
- SIRT1
- Gene Alias:
- SIR2L1
- Gene Description:
- sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae)
- Omim ID:
- 604479
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq
- Other Designations:
- OTTHUMP00000019691,OTTHUMP00000060745,SIR2alpha,sir2-like 1,sirtuin 1,sirtuin type 1
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