TFPI monoclonal antibody
产品名称: TFPI monoclonal antibody
英文名称: TFPI monoclonal antibody
产品编号: MAB0281
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against synthetic peptide of TFPI.
- Immunogen:
- A synthetic peptide corresponding to 16 amino acids at N-terminus of human TFPI.
- Sequence:
- Asp-Ser-Glu-Glu-Asp-Glu-Glu-His-Thr-Ile-Ile-Thr-Asp-Thr-Glu-Cys
- Host:
- Mouse
- Reactivity:
- Human
- Specificity:
- This antibody recognizes human tissue factor pathway inhibitor.
- Form:
- Liquid
- Purity:
- > 95% by SDS-PAGE
- Isotype:
- IgG
- Storage Buffer:
- In PBS (50% glycerol)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (5 ug/mL)
The optimal working dilution should be determined by the end user.
- Application Image
- Western Blot
- ELISA
- Entrez GeneID:
- 7035
- Gene Name:
- TFPI
- Gene Alias:
- EPI,LACI,TFI,TFPI1
- Gene Description:
- tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
- Omim ID:
- 152310
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. The encoded protein is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been confirmed. [provided by RefSeq
- Other Designations:
- OTTHUMP00000163472,anti-convertin,extrinsic pathway inhibitor,lipoprotein-associated coagulation inhibitor,tissue factor pathway inhibitor
- Gene Pathway
- Related Disease
- Acute Disease
- Antiphospholipid Syndrome
- Arterial Occlusive Diseases
- Atherosclerosis
- Atherosclerosis
- Autistic Disorder
- Brain Ischemia
- Cadaver
- Cardiovascular Diseases
- Cerebral Infarction
- Cerebral Palsy
- Cerebrovascular Accident
- Coronary Disease
- Coronary Restenosis
- Diabetes Mellitus, Type 2
- Edema
- Femur Head Necrosis
- Genetic Predisposition to Disease
- Hemorrhage