GCN5L2 polyclonal antibody
产品名称： GCN5L2 polyclonal antibody
英文名称： GCN5L2 polyclonal antibody
产品编号： PAB2243
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of GCN5L2.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human GCN5L2.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- GCN5: a supervisor in all-inclusive control of vertebrate cell cycle progression through transcription regulation of various cell cycle-related genes.
Kikuchi H, Takami Y, Nakayama T.Gene. 2005 Feb 28;347(1):83-97.
- 2.
- The transforming acidic coiled coil proteins interact with nuclear histone acetyltransferases.
Gangisetty O, Lauffart B, Sondarva GV, Chelsea DM, Still IH.Oncogene. 2004 Apr 1;23(14):2559-63.
- 3.
- Regulation of HIV-1 gene expression by histone acetylation and factor recruitment at the LTR promoter.
Lusic M, Marcello A, Cereseto A, Giacca M.EMBO J. 2003 Dec 15;22(24):6550-61.
- Entrez GeneID:
- 2648
- Protein Accession#:
- NP_066564;Q8N1A2
- Gene Name:
- KAT2A
- Gene Alias:
- GCN5,GCN5L2,MGC102791,PCAF-b,hGCN5
- Gene Description:
- K(lysine) acetyltransferase 2A
- Omim ID:
- 602301
- Gene Ontology:
- Hyperlink
- Gene Summary:
- KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009 [PubMed 19339690]).[supplied by OMIM
- Other Designations:
- GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 2,GCN5 general control of amino-acid synthesis 5-like 2,General control of amino acid synthesis, yeast, homolog-like 2
- Gene Pathway
- Related Disease