TNFRSF10B polyclonal antibody
产品名称： TNFRSF10B polyclonal antibody
英文名称： TNFRSF10B polyclonal antibody
产品编号： PAB14350
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against recombinant TNFRSF10B.
- Immunogen:
- Recombinant protein corresponding to human TNFRSF10B.
- Host:
- Rabbit
- Reactivity:
- Human
- Specificity:
- human DR5.
- Form:
- Liquid
- Storage Buffer:
- In 100 mM BBS, pH 8.2
- Storage Instruction:
- Store at 4°C.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Publication Reference
- 1.
- 2-methoxyestradiol up-regulates death receptor 5 and induces apoptosis through activation of the extrinsic pathway.
LaVallee TM, Zhan XH, Johnson MS, Herbstritt CJ, Swartz G, Williams MS, Hembrough WA, Green SJ, Pribluda VS.Cancer Res. 2003 Jan 15;63(2):468-75.
- 2.
- Pretreatment with paclitaxel enhances apo-2 ligand/tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of prostate cancer cells by inducing death receptors 4 and 5 protein levels.
Nimmanapalli R, Perkins CL, Orlando M, O'Bryan E, Nguyen D, Bhalla KN.Cancer Res. 2001 Jan 15;61(2):759-63.
- 3.
- An antagonist decoy receptor and a death domain-containing receptor for TRAIL.
Pan G, Ni J, Wei YF, Yu G, Gentz R, Dixit VM.Science. 1997 Aug 8;277(5327):815-8.
- Entrez GeneID:
- 8795
- Gene Name:
- TNFRSF10B
- Gene Alias:
- CD262,DR5,KILLER,KILLER/DR5,TRAIL-R2,TRAILR2,TRICK2,TRICK2A,TRICK2B,TRICKB,ZTNFR9
- Gene Description:
- tumor necrosis factor receptor superfamily, member 10b
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq
- Other Designations:
- Fas-like protein,OTTHUMP00000123492,TNF-related apoptosis-inducing ligand receptor 2,TRAIL receptor 2,apoptosis inducing protein TRICK2A/2B,apoptosis inducing receptor TRAIL-R2,cytotoxic TRAIL receptor-2,death domain containing receptor for TRAIL/Apo-2L,d
- Related Disease
- Asthma
- Breast Neoplasms
- Carcinoma, Ductal
- Carcinoma, Squamous Cell
- Cardiovascular Diseases
- Cleft Lip
- Cleft Palate
- Colorectal Neoplasms
- Diabetes Mellitus, Type 2
- Disease Progression
- Edema
- Genetic Predisposition to Disease
- Head and Neck Neoplasms
- Hematologic Diseases
- Hodgkin Disease
- Lymphoproliferative Disorders
- Multiple Myeloma
- Neoplasm Metastasis
- Neoplasms, Second Primary