PIK3C2A polyclonal antibody
产品名称： PIK3C2A polyclonal antibody
英文名称： PIK3C2A polyclonal antibody
产品编号： PAB6593
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of PIK3C2A.
- Immunogen:
- A synthetic peptide corresponding to human PIK3C2A.
- Sequence:
- C-TVKWYQLTAATYL
- Host:
- Goat
- Theoretical MW (kDa):
- 191
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- ELISA (1:32000)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5-10 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Cpk is a novel class of Drosophila PtdIns 3-kinase containing a C2 domain.
Molz L, Chen YW, Hirano M, Williams LT.J Biol Chem. 1996 Jun 7;271(23):13892-9.
- Application Image
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- ELISA
- Entrez GeneID:
- 5286
- Protein Accession#:
- NP_002636
- Gene Name:
- PIK3C2A
- Gene Alias:
- CPK,DKFZp686L193,MGC142218,PI3-K-C2(ALPHA),PI3-K-C2A
- Gene Description:
- phosphoinositide-3-kinase, class 2, alpha polypeptide
- Omim ID:
- 603601
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling. [provided by RefSeq
- Other Designations:
- C2-containing phosphatidylinositol kinase,PI3K-C2alpha