APOE polyclonal antibody-抗体-抗体-生物在线

产品名称： APOE polyclonal antibody

英文名称： APOE polyclonal antibody

产品编号： PAB18003

产品价格： null

产品产地：台湾

品牌商标： Abnova

更新时间： null

使用范围：

亚诺法生技股份有限公司（Abnova)

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Storage Instruction:
Store at -20°C. For long term storage store at -80°.
Aliquot to avoid repeated freezing and thawing.

Recommend Usage:
Western Blot (0.5-4 ug/mL)
The optimal working dilution should be determined by the end user.

Note:
This product contains thimerosal: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Gene Summary:
Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq