TFF3 monoclonal antibody (M01), clone 3D9
产品名称： TFF3 monoclonal antibody (M01), clone 3D9
英文名称： TFF3 monoclonal antibody (M01), clone 3D9
产品编号： H00007033-M01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a full length recombinant TFF3.
- Immunogen:
- TFF3 (AAH17859.1, 15 a.a. ~ 73 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- EEYVGLSANQCAVPAKDRVDCGYPHVTPKECNNRGCCFDSRIPGVPWCFKPLQEAECTF
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG1 Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (32.23 KDa) .
- MSDS:
Download
- Publication Reference
- 1.
- Fresh and cryopreserved amniotic membrane secrete the trefoil factor family peptide 3 that is well known to promote wound healing.
Schulze U, Hampel U, Sel S, Goecke TW, Thale V, Garreis F, Paulsen F.Histochem Cell Biol. 2012 Apr 3. [Epub ahead of print]
- 2.
- Profiling of differentially expressed proteins in stage IV Colorectal cancers with good and poor outcomes.
Kim HJ, Kang UB, Lee H, Jung JH, Lee ST, Yu MH, Kim H, Lee C.J Proteomics. 2011 Dec 10.
- 3.
- Genetic predisposition directs breast cancer phenotype by dictating progenitor cell fate.
Proia TA, Keller PJ, Gupta PB, Klebba I, Jones AD, Sedic M, Gilmore H, Tung N, Naber SP, Schnitt S, Lander ES, Kuperwasser C.Cell Stem Cell. 2011 Feb 4;8(2):149-63.
- 4.
- Identification of serum biomarkers for colorectal cancer metastasis using a differential secretome approach.
Xue H, Lu B, Zhang J, Wu M, Huang Q, Wu Q, Sheng H, Wu D, Hu J, Lai M.J Proteome Res. 2010 Jan;9(1):545-55.
- 5.
- Trefoil factor 3: a novel serum marker identified by gene expression profiling in high-grade endometrial carcinomas.
Bignotti E, Ravaggi A, Tassi RA, Calza S, Rossi E, Falchetti M, Romani C, Bandiera E, Odicino FE, Pecorelli S, Santin AD.Br J Cancer. 2008 Sep 2;99(5):768-73.
- Applications
- Western Blot (Recombinant protein)
- Protocol Download
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
enlarge this image- Immunoperoxidase of monoclonal antibody to TFF3 on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 3 ug/ml]
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged TFF3 is approximately 0.03ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 7033
- GeneBank Accession#:
- BC017859
- Protein Accession#:
- AAH17859.1
- Gene Name:
- TFF3
- Gene Alias:
- HITF,ITF,TFI,hP1.B
- Gene Description:
- trefoil factor 3 (intestinal)
- Omim ID:
- 600633
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. This gene is expressed in goblet cells of the intestines and colon. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq
- Other Designations:
- intestinal trefoil factor,secretory protein,trefoil factor 3,trefoil factor 3, HITF, human intestinal trefoil factor