ACVR1C (Center) Peptide
产品名称： ACVR1C (Center) Peptide
英文名称： ACVR1C (Center) Peptide
产品编号： P2243
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of ACVR1C.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to internal region of human ACVR1C.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Purification:
- Ammonium sulfate precipitation
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Nodal and ALK7 inhibit proliferation and induce apoptosis in human trophoblast cells.
Munir S, Xu G, Wu Y, Yang B, Lala PK, Peng C.J Biol Chem. 2004 Jul 23;279(30):31277-86. Epub 2004 May 18.
- 2.
- Activin receptor-like kinase-7 induces apoptosis through activation of MAPKs in a Smad3-dependent mechanism in hepatoma cells.
Kim BC, van Gelder H, Kim TA, Lee HJ, Baik KG, Chun HH, Lee DA, Choi KS, Kim SJ.J Biol Chem. 2004 Jul 2;279(27):28458-65. Epub 2004 Apr 23.
- 3.
- Identification of novel isoforms of activin receptor-like kinase 7 (ALK7) generated by alternative splicing and expression of ALK7 and its ligand, Nodal, in human placenta.
Roberts HJ, Hu S, Qiu Q, Leung PC, Caniggia I, Gruslin A, Tsang B, Peng C.Biol Reprod. 2003 May;68(5):1719-26. Epub 2002 Dec 27.
- Entrez GeneID:
- 130399
- Protein Accession#:
- NP_660302;Q8NER5
- Gene Name:
- ACVR1C
- Gene Alias:
- ACVRLK7,ALK7
- Gene Description:
- activin A receptor, type IC
- Omim ID:
- 608981
- Gene Ontology:
- Hyperlink
- Gene Summary:
- ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM
- Other Designations:
- activin receptor-like kinase 7
- Interactome
