LITAF polyclonal antibody
产品名称： LITAF polyclonal antibody
英文名称： LITAF polyclonal antibody
产品编号： PAB7572
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of LITAF.
- Immunogen:
- A synthetic peptide corresponding to human LITAF.
- Sequence:
- C-PDGKGMNPPSYYTQ
- Host:
- Goat
- Theoretical MW (kDa):
- 17.1, 15.8
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- ELISA (1:8000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- LPS-induced TNF-alpha factor (LITAF)-deficient mice express reduced LPS-induced cytokine: Evidence for LITAF-dependent LPS signaling pathways.
Tang X, Metzger D, Leeman S, Amar S.Proc Natl Acad Sci U S A. 2006 Sep 12;103(37):13777-82. Epub 2006 Sep 5.
- Application Image
- ELISA
- Entrez GeneID:
- 9516
- Protein Accession#:
- NP_004853.2
- Gene Name:
- LITAF
- Gene Alias:
- FLJ38636,MGC116698,MGC116700,MGC116701,MGC125274,MGC125275,MGC125276,PIG7,SIMPLE,TP53I7
- Gene Description:
- lipopolysaccharide-induced TNF factor
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppresor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq
- Other Designations:
- LPS-induced TNF-alpha factor,lipopolysaccharide-induced TNF-alpha factor,lipopolysaccharide-induced tumor necrosis factor-alpha factor,p53-induced gene 7 protein,small integral membrane protein of lysosome/late endosome,tumor protein p53 inducible protein