Abi-1 Antibody
产品名称: Abi-1 Antibody
英文名称: Abi-1 Antibody
产品编号: 251822
产品价格: null
产品产地: 美国
品牌商标: Abbiotec
更新时间: null
使用范围: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500; ICC: 1:100-1:500
深圳市豪地华拓生物科技有限公司
- 联系人 :
- 地址 : 深圳市南山创业路中兴城5栋518
- 邮编 : 518054
- 所在区域 : 广东
- 电话 : 132****4656 点击查看
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- 邮箱 : order@otwobiotech.com
Abelson interactor 1 (Abi-1) negatively regulates cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. Abi-1 plays a role in regulation of EGF-induced Erk pathway activation. Abi-1 is involved in cytoskeletal reorganization and EGFR signaling, and together with EPS8 participates in transduction of signals from Ras to Rac. A chromosomal aberration involving Abi-1 is a cause of acute leukemias.