MAP4K4 (phospho S801) Peptide
产品名称： MAP4K4 (phospho S801) Peptide
英文名称： MAP4K4 (phospho S801) Peptide
产品编号： P1579
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of MAP4K4.
- Immunogen:
- Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S801 of human MAP4K4.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Peptide affinity purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Dot Blot (1:500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- The STE20 kinase HGK is broadly expressed in human tumor cells and can modulate cellular transformation, invasion, and adhesion.
Wright JH, Wang X, Manning G, LaMere BJ, Le P, Zhu S, Khatry D, Flanagan PM, Buckley SD, Whyte DB, Howlett AR, Bischoff JR, Lipson KE, Jallal B.Mol Cell Biol. 2003 Mar;23(6):2068-82.
- 2.
- A novel human STE20-related protein kinase, HGK, that specifically activates the c-Jun N-terminal kinase signaling pathway.
Yao Z, Zhou G, Wang XS, Brown A, Diener K, Gan H, Tan TH.J Biol Chem. 1999 Jan 22;274(4):2118-25.
- 3.
- Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.
Ishikawa K, Nagase T, Suyama M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O.DNA Res. 1998 Jun 30;5(3):169-76.
- Entrez GeneID:
- 9448
- Protein Accession#:
- O95819
- Gene Name:
- MAP4K4
- Gene Alias:
- FLH21957,FLJ10410,FLJ20373,FLJ90111,HGK,KIAA0687,NIK
- Gene Description:
- mitogen-activated protein kinase kinase kinase kinase 4
- Omim ID:
- 604666
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
- Other Designations:
- HPK/GCK-like kinase,hepatocyte progenitor kinase-like/germinal center kinase-like kinase
- Gene Pathway