SNAP25 monoclonal antibody, clone 4E11
产品名称： SNAP25 monoclonal antibody, clone 4E11
英文名称： SNAP25 monoclonal antibody, clone 4E11
产品编号： MAB1105
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against full length recombinant SNAP25.
- Immunogen:
- Recombinant protein corresponding to full length human SNAP25.
- Host:
- Mouse
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Isotype:
- IgG1, kappa
- Storage Buffer:
- In PBS, pH 7.4 (0.1% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:1000-1:3000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Expression and function of SNAP-25 as a universal SNARE component in GABAergic neurons.
Tafoya LC, Mameli M, Miyashita T, Guzowski JF, Valenzuela CF, Wilson MC.J Neurosci. 2006 Jul 26;26(30):7826-38.
- 2.
- Increased association of synaptosome-associated protein of 25 kDa with syntaxin and vesicle-associated membrane protein following acrosomal exocytosis of sea urchin sperm.
Schulz JR, Sasaki JD, Vacquier VD.J Biol Chem. 1998 Sep 18;273(38):24355-9.
- Applications
- Western Blot (Tissue lysate)
- Western blot analysis of mouse brain extracts (30 ug) were resolved by SDS - PAGE , transferred to NC membrane and probed with SNAP25 monoclonal antibody , clone 4E11 (1 : 2000) (Cat # MAB1105). Proteins were visualized using a goat anti - mouse secondary antibody conjugated to HRP and an ECL detection system.
- Entrez GeneID:
- 6616
- GeneBank Accession#:
- NM_130811
- Protein Accession#:
- NP_570824
- Gene Name:
- SNAP25
- Gene Alias:
- FLJ23079,RIC-4,RIC4,SEC9,SNAP,SNAP-25,bA416N4.2,dJ1068F16.2
- Gene Description:
- synaptosomal-associated protein, 25kDa
- Omim ID:
- 600322
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq
- Other Designations:
- OTTHUMP00000030267,OTTHUMP00000030268,resistance to inhibitors of cholinesterase 4 homolog,synaptosomal-associated protein 25
- Gene Pathway
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Attention
- Attention Deficit Disorder with Hyperactivity
- Autistic Disorder
- Bipolar Disorder
- Cardiovascular Diseases
- Cognition
- Cognition Disorders
- Depressive Disorder, Major
- Diabetes Complications
- Epilepsy
- Epilepsy
- Genetic Predisposition to Disease
- Memory
- Mental Disorders
- Mental Retardation
- Metabolic Syndrome X
- Narcolepsy