CAMK2A (phospho T286) polyclonal antibody
产品名称： CAMK2A (phospho T286) polyclonal antibody
英文名称： CAMK2A (phospho T286) polyclonal antibody
产品编号： PAB10934
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of CAMK2A.
- Immunogen:
- Synthetic phosphopeptide corresponding to residues surrounding T286 of human CAMK2A.
- Host:
- Rabbit
- Theoretical MW (kDa):
- 50
- Reactivity:
- Human, Mouse, Rat
- Form:
- Liquid
- Purification:
- Immunoaffinity purification
- Concentration:
- 1 mg/mL
- Storage Buffer:
- In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- The stability of a stochastic CaMKII switch: dependence on the number of enzyme molecules and protein turnover.
Miller P, Zhabotinsky AM, Lisman JE, Wang XJ.PLoS Biol. 2005 Apr;3(4):e107. Epub 2005 Mar 29.
- 2.
- A role for prefrontal calcium-sensitive protein phosphatase and kinase activities in working memory.
Runyan JD, Moore AN, Dash PK.Learn Mem. 2005 Mar-Apr;12(2):103-10.
- 3.
- Involvement of neurogranin in the modulation of calcium/calmodulin-dependent protein kinase II, synaptic plasticity, and spatial learning: a study with knockout mice.
Pak JH, Huang FL, Li J, Balschun D, Reymann KG, Chiang C, Westphal H, Huang KP.Proc Natl Acad Sci U S A. 2000 Oct 10;97(21):11232-7.
- Entrez GeneID:
- 815
- Protein Accession#:
- P11798
- Gene Name:
- CAMK2A
- Gene Alias:
- CAMKA,KIAA0968
- Gene Description:
- calcium/calmodulin-dependent protein kinase II alpha
- Omim ID:
- 114078
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq
- Other Designations:
- CaM kinase II alpha subunit,CaM-kinase II alpha chain,CaMK-II alpha subunit,CaMKIINalpha,OTTHUMP00000165787,OTTHUMP00000165788,calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha,calcium/calmodulin-dependent protein kinase II alpha-B subunit
- Interactome
