CASP4 polyclonal antibody
产品名称： CASP4 polyclonal antibody
英文名称： CASP4 polyclonal antibody
产品编号： PAB9824
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of CASP4.
- Immunogen:
- A synthetic peptide corresponding to N-terminus of human CASP4.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Storage Buffer:
- In PBS (0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- Western Blot (1 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases.
Martinon F, Tschopp J.Cell. 2004 May 28;117(5):561-74.
- 2.
- Interleukin-18.
Gracie JA, Robertson SE, McInnes IB.J Leukoc Biol. 2003 Feb;73(2):213-24.
- 3.
- Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme.
Kuida K, Lippke JA, Ku G, Harding MW, Livingston DJ, Su MS, Flavell RA.Science. 1995 Mar 31;267(5206):2000-3.
- Entrez GeneID:
- 837
- Gene Name:
- CASP4
- Gene Alias:
- ICE(rel)II,ICEREL-II,ICH-2,Mih1/TX,TX
- Gene Description:
- caspase 4, apoptosis-related cysteine peptidase
- Omim ID:
- 602664
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq
- Other Designations:
- apoptotic cysteine protease Mih1/TX,caspase 4,caspase 4, apoptosis-related cysteine protease