PCSK9 polyclonal antibody
产品名称: PCSK9 polyclonal antibody
英文名称: PCSK9 polyclonal antibody
产品编号: PAB18962
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of PCSK9.
- Immunogen:
- A synthetic peptide corresponding to amino acids at internal region of human PCSK9.
- Sequence:
- TRFHRQASKCDSHGT
- Host:
- Goat
- Theoretical MW (kDa):
- 80-100
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In 0.5 mg/mL in Tris saline, pH7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:16000)
Western Blot (0.1-0.5 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
- Western Blot (Transfected lysate)
- HEK293 lysate (10 ug protein in RIPA buffer) overexpressing human PCSK9 with C-terminal MYC tag probed with PCSK9 polyclonal antibody (Cat # PAB18962, 1 ug/mL) in Lane A and probed with anti-MYC Tag (1/1000) in lane C. Mock-transfected HEK293 probed with PCSK9 polyclonal antibody (Cat # PAB18962, 1 mg/mL) in Lane B. Primary incubations were for 1 hour. Detected by chemiluminescence.
- Entrez GeneID:
- 255738
- Protein Accession#:
- NP_777596.2
- Gene Name:
- PCSK9
- Gene Alias:
- FH3,HCHOLA3,LDLCQ1,NARC-1,NARC1
- Gene Description:
- proprotein convertase subtilisin/kexin type 9
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. The encoded protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. This protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a third form of autosomal dominant familial hypercholesterolemia (HCHOLA3). [provided by RefSeq
- Other Designations:
- OTTHUMP00000009833,convertase subtilisin/kexin type 9 preproprotein,neural apoptosis regulated convertase 1
- Related Disease
- Alzheimer Disease
- Atherosclerosis
- Atherosclerosis
- Calcinosis
- Cardiovascular Diseases
- Chromosome Aberrations
- Chronic Disease
- Coronary Artery Disease
- Coronary Disease
- Dementia
- Diabetes Mellitus, Type 2
- Edema
- Genetic Predisposition to Disease
- Hypercholesterolemia
- Hyperlipoproteinemia Type II
- Hypertension
- Hypobetalipoproteinemias
- Hypolipoproteinemias
- Kidney Diseases