VAV1 monoclonal antibody (M03), clone 2C11
产品名称： VAV1 monoclonal antibody (M03), clone 2C11
英文名称： VAV1 monoclonal antibody (M03), clone 2C11
产品编号： H00007409-M03
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant VAV1.
- Immunogen:
- VAV1 (AAH13361, 681 a.a. ~ 790 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- RGLTELVEFYQQNSLKDCFKSLDTTLQFPFKEPEKRTISRPAVGSTKYFGTAKARYDFCARDRSELSLKEGDIIKILNKKGQQGWWRGEIYGRVGWFPANYVEEDYSEYC
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2a Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.84 KDa) .
- MSDS:
Download
- Applications
- Western Blot (Cell lysate)
- VAV1 monoclonal antibody (M03), clone 2C11 Western Blot analysis of VAV1 expression in Jurkat ( Cat # L017V1 ).
- Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged VAV1 is approximately 0.1ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 7409
- GeneBank Accession#:
- BC013361
- Protein Accession#:
- AAH13361
- Gene Name:
- VAV1
- Gene Alias:
- VAV
- Gene Description:
- vav 1 guanine nucleotide exchange factor
- Omim ID:
- 164875
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this proto-oncogene is a member of the Dbl family of guanine nucleotide exchange factors (GEF) for the Rho family of GTP binding proteins. The protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. This particular GEF has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. [provided by RefSeq
- Other Designations:
- oncogene vav,vav 1 oncogene,vav proto-oncogene