CASP8 (Human) ELISA Kit
产品名称: CASP8 (Human) ELISA Kit
英文名称: CASP8 (Human) ELISA Kit
产品编号: KA0184
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
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- Specification
- Product Description:
- CASP8 (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human caspase8/FLICE.
- Calibration Range:
- 0.16 to 10 ng/mL
- Limit of Detection:
- 0.1 ng/mL
- Reactivity:
- Human
- Storage Instruction:
- Store the kit at 4°C.
- Quality Control Testing:
- Standard curve
The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
- Protocol:
- Protocol Download
- MSDS:
- Download
- Suitable Sample:
- Cell Culture Supernatant, Cell Lysate, Serum
- Sample Volume:
- 50 uL
- Label:
- HRP-conjugate
- Detection Method:
- Colorimetric
- Intra-Assay:
- 6.70%
- Inter-Assay:
- 8.50%
- Spiking Recovery:
- 89.50%
- Regulation Status:
- For research use only (RUO)
- Application Image
- Quantification
- Entrez GeneID:
- 841
- Gene Name:
- CASP8
- Gene Alias:
- ALPS2B,CAP4,FLICE,FLJ17672,MACH,MCH5,MGC78473
- Gene Description:
- caspase 8, apoptosis-related cysteine peptidase
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This protein is involved in the programmed cell death induced by Fas and various apoptotic stimuli. The N-terminal FADD-like death effector domain of this protein suggests that it may interact with Fas-interacting protein FADD. This protein was detected in the insoluble fraction of the affected brain region from Huntington disease patients but not in those from normal controls, which implicated the role in neurodegenerative diseases. Many alternatively spliced transcript variants encoding different isoforms have been described, although not all variants have had their full-length sequences determined. [provided by RefSeq
- Other Designations:
- FADD-homologous ICE/CED-3-like protease,MACH-alpha-1/2/3 protein,MACH-beta-1/2/3/4 protein,Mch5 isoform alpha,OTTHUMP00000163718,OTTHUMP00000163719,OTTHUMP00000163720,caspase 8,caspase 8, apoptosis-related cysteine protease,cysteine protease,procaspase-8
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