SERPINE1 polyclonal antibody
产品名称： SERPINE1 polyclonal antibody
英文名称： SERPINE1 polyclonal antibody
产品编号： PAB6774
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of SERPINE1.
- Immunogen:
- A synthetic peptide corresponding to internal region of human SERPINE1.
- Sequence:
- C-GFKIDDKGMAPALRH
- Host:
- Goat
- Theoretical MW (kDa):
- 45.1
- Reactivity:
- Human
- Specificity:
- This antibody is expected to recognise both reported isoforms.
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:64000)
Sandwhich ELISA (1.5-3 ug/mL)
Western Blot (0.3-1 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (4-6 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Activation of mast cells by incorporation of cholesterol into rafts.
Baumruker T, Csonga R, Pursch E, Pfeffer A, Urtz N, Sutton S, Bofill-Cardona E, Cooke M, Prieschl E.Int Immunol. 2003 Oct;15(10):1207-18.
- Applications
- Western Blot (Tissue lysate)
- SERPINE1 polyclonal antibody (Cat # PAB6774) (0.1 ug/mL) staining of human liver lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
- Entrez GeneID:
- 5054
- Protein Accession#:
- NP_000593.1;NP_001158885.1
- Gene Name:
- SERPINE1
- Gene Alias:
- PAI,PAI-1,PAI1,PLANH1
- Gene Description:
- serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
- Omim ID:
- 173360
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- plasminogen activator inhibitor, type I,plasminogen activator inhibitor-1,serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
- Related Disease
- Abortion, Habitual
- Abortion, Spontaneous
- Activated Protein C Resistance
- Acute Disease
- Acute Lung Injury
- Acute-Phase Reaction
- Adenocarcinoma
- Adenomatous Polyposis Coli
- Albuminuria
- alpha 1-Antitrypsin Deficiency
- Alpha-1-antitrypsin deficiency
- Alveolar Bone Loss
- Alzheimer Disease
- Alzheimer disease
- Amyloidosis
- Amyotrophic Lateral Sclerosis
- Amyotrophic lateral sclerosis
- Anemia, Sickle Cell
- Anemia, sickle cell