IL15 monoclonal antibody (M15), clone 1A5
产品名称: IL15 monoclonal antibody (M15), clone 1A5
英文名称: IL15 monoclonal antibody (M15), clone 1A5
产品编号: H00003600-M15
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a full length recombinant IL15.
- Immunogen:
- IL15 (NP_000576, 49 a.a. ~ 162 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- NWVNVISDLKKIEDLIQSMHIDATLYTESDVHPSCKVTAMKCFLLELQVISLESGDASIHDTVENLIILANNSLSSNGNVTESGCKECEELEEKNIKEFLQSFVHIVQMFINTS
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG1 Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- MSDS:
- Download
- Applications
- Immunofluorescence
- enlarge this image
- Immunofluorescence of monoclonal antibody to IL15 on HeLa cell . [antibody concentration 10 ug/ml]
- Protocol Download
- Entrez GeneID:
- 3600
- GeneBank Accession#:
- NM_000585
- Protein Accession#:
- NP_000576
- Gene Name:
- IL15
- Gene Alias:
- IL-15,MGC9721
- Gene Description:
- interleukin 15
- Omim ID:
- 600554
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported. [provided by RefSeq
- Other Designations:
- OTTHUMP00000164617
- Related Disease
- Adenocarcinoma
- Arthritis, Rheumatoid
- Asthma
- Asthma
- Bronchial Hyperreactivity
- Bronchiolitis, Viral
- Carcinoma, Non-Small-Cell Lung
- Cardiovascular Diseases
- Celiac Disease
- Connective Tissue Diseases
- Coronary Disease
- Diabetes Mellitus
- Diabetes Mellitus, Type 2
- Edema
- Esophageal Neoplasms
- Fetal Diseases
- Fractures, Bone
- Genetic Predisposition to Disease
- Hematologic Diseases