HSP90 monoclonal antibody, clone 8D3
产品名称： HSP90 monoclonal antibody, clone 8D3
英文名称： HSP90 monoclonal antibody, clone 8D3
产品编号： MAB6620
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against HSP90.
- Immunogen:
- Ah receptor (Aryl hydrocarbon receptor).
- Host:
- Mouse
- Reactivity:
- Human, Mouse, Rabbit, Rat
- Specificity:
- Immunoprecipitates 90KDa proteins corresponding to the molecular mass of Hsp90. Co-immunoprecipitates Hsp90 complexes, including Hsp70, Hop, Ah receptors, glucocorticoid receptors, heme-regulated eukaryotic initiation factor 2alpha (eIF-2alpha) kinase (HRI).
- Form:
- Liquid
- Isotype:
- IgM
- Storage Buffer:
- In PBS (0.09% sodium azide, 50% glycerol)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Hsp90 inhibition depletes Chk1 and sensitizes tumor cells to replication stress.
Arlander SJ, Eapen AK, Vroman BT, McDonald RJ, Toft DO, Karnitz LM.J Biol Chem. 2003 Dec 26;278(52):52572-7. Epub 2003 Oct 21.
- 2.
- Hsp90 inhibitors as novel cancer chemotherapeutic agents.
Neckers L.Trends Mol Med. 2002;8(4 Suppl):S55-61.
- 3.
- Inhibition of heat shock protein HSP90-pp60v-src heteroprotein complex formation by benzoquinone ansamycins: essential role for stress proteins in oncogenic transformation.
Whitesell L, Mimnaugh EG, De Costa B, Myers CE, Neckers LM.Proc Natl Acad Sci U S A. 1994 Aug 30;91(18):8324-8.
- Application Image
- Immunoprecipitation