C2 (Human) Recombinant Protein (Q01)
产品名称： C2 (Human) Recombinant Protein (Q01)
英文名称： C2 (Human) Recombinant Protein (Q01)
产品编号： H00000717-Q01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
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- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human C2 partial ORF (NP_000054.2, 21 a.a. - 243 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- APSCPQNVNISGGTFTLSHGWAPGSLLTYSCPQGLYPSPASRLCKSSGQWQTPGATRSLSKAVCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICRQPYSYDFPEDVAPALGTSFSHMLGATNPTQKTKESLGR
- Theoretical MW (kDa):
- 50.16
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 717
- GeneBank Accession#:
- NM_000063.3
- Protein Accession#:
- NP_000054.2
- Gene Name:
- C2
- Gene Alias:
- CO2,DKFZp779M0311
- Gene Description:
- complement component 2
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined
- Other Designations:
- C3/C5 convertase,OTTHUMP00000029277,OTTHUMP00000062690,complement C2,complement component C2
- Related Disease
- Atherosclerosis
- Autoimmune Diseases
- Birth Weight
- Calcinosis
- Cardiovascular Diseases
- Choroid Diseases
- Choroidal Neovascularization
- Coronary Aneurysm
- Coronary Artery Disease
- Coronary Disease
- Crohn's disease
- Cross Infection
- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Type 2
- Disease Models, Animal
- Disease Progression
- Diseases in Twins
- Edema
- Genetic Predisposition to Disease