GSTA1 MaxPab mouse polyclonal antibody (B01)
产品名称: GSTA1 MaxPab mouse polyclonal antibody (B01)
英文名称: GSTA1 MaxPab mouse polyclonal antibody (B01)
产品编号: H00002938-B01
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a full-length human GSTA1 protein.
- Immunogen:
- GSTA1 (NP_665683.1, 1 a.a. ~ 222 a.a) full-length human protein.
- Sequence:
- MAEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDAKLALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEEARKIFRF
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- No additive
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- Note:
- For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
- MSDS:
- Download
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of GSTA1 expression in transfected 293T cell line (H00002938-T02) by GSTA1 MaxPab polyclonal antibody.
Lane 1: GSTA1 transfected lysate(25.60 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Entrez GeneID:
- 2938
- GeneBank Accession#:
- NM_145740.2
- Protein Accession#:
- NP_665683.1
- Gene Name:
- GSTA1
- Gene Alias:
- GST2,GSTA1-1,GTH1,MGC131939
- Gene Description:
- glutathione S-transferase alpha 1
- Omim ID:
- 138359
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation. [provided by RefSeq
- Other Designations:
- GST, class alpha, 1,GST-epsilon,OTTHUMP00000016611,S-(hydroxyalkyl)glutathione lyase A1,glutathione S-alkyltransferase A1,glutathione S-aryltransferase A1,glutathione S-transferase 2,glutathione S-transferase A1,glutathione S-transferase Ha subunit 1
- Related Disease
- Acute Disease
- Adenoma
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- Alzheimer disease
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- Asthma
- Breast cancer
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- Carcinoma
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- Carcinoma, Hepatocellular
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- Chromosome Deletion