XRCC3 polyclonal antibody
产品名称： XRCC3 polyclonal antibody
英文名称： XRCC3 polyclonal antibody
产品编号： PAB11977
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of XRCC3.
- Immunogen:
- A synthetic peptide corresponding to human XRCC3.
- Host:
- Rabbit
- Reactivity:
- Human
- Specificity:
- This antibody is specific to XRCC3.
- Form:
- Liquid
- Storage Buffer:
- In PBS (0.05% sodium azide)
- Storage Instruction:
- Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- Western Blot (1:5000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Xrcc3 and Nbs1 are required for the production of extrachromosomal telomeric circles in human alternative lengthening of telomere cells.
Compton SA, Choi JH, Cesare AJ, Ozgur S, Griffith JD.Cancer Res. 2007 Feb 15;67(4):1513-9.
- 2.
- Differential regulation of short- and long-tract gene conversion between sister chromatids by Rad51C.
Nagaraju G, Odate S, Xie A, Scully R.Mol Cell Biol. 2006 Nov;26(21):8075-86. Epub 2006 Sep 5.
- 3.
- Role for RAD18 in homologous recombination in DT40 cells.
Szuts D, Simpson LJ, Kabani S, Yamazoe M, Sale JE.Mol Cell Biol. 2006 Nov;26(21):8032-41. Epub 2006 Aug 21.
- 4.
- XRCC3 deficiency results in a defect in recombination and increased endoreduplication in human cells.
Yoshihara T, Ishida M, Kinomura A, Katsura M, Tsuruga T, Tashiro S, Asahara T, Miyagawa K.EMBO J. 2004 Feb 11;23(3):670-80. Epub 2004 Jan 29.
- Entrez GeneID:
- 7517
- Gene Name:
- XRCC3
- Gene Alias:
- -
- Gene Description:
- X-ray repair complementing defective repair in Chinese hamster cells 3
- Omim ID:
- 600675
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq
- Other Designations:
- DNA repair protein XRCC3,RAD51-like,X-ray repair cross complementing protein 3,X-ray-repair, complementing defective, repair in Chinese hamster
- Gene Pathway
- Related Disease
- Adenocarcinoma
- Adenoma
- Astrocytoma
- Ataxia telangiectasia
- Barrett Esophagus
- Biliary Tract Neoplasms
- Bone Neoplasms
- Brain Neoplasms
- Breast cancer
- Breast Neoplasms
- Carcinoma
- Carcinoma, Basal Cell
- Carcinoma, Ductal
- Carcinoma, Ductal, Breast
- Carcinoma, Hepatocellular
- Carcinoma, Lobular
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Pancreatic Ductal
- Carcinoma, Papillary