Product Information
    
 
    

    

        

            

                

                
Product Name
                
                

                
Cat#
                
                

                
Size
                
                

                
Price（¥）
                
            
            

                

                
Recombinant Mouse Interleukin-13 (Mouse IL-13)
                
                

                
90151ES10
                
                

                
10 μg
                
                

                
1855.00
                
            
            

                

                
90151ES60
                
                

                
100 μg
                
                

                
13615.00
                
            
            

                

                
90151ES76
                
                

                
500 μg
                
                

                
35395.00
                
            
        
    
    
    
 
    
Product Description
    
 
    
Interleukin-13 (IL-13) was first recognized for its effects on B cells and monocytes, where it upregulated class II expression, promoted IgE class switching and inhibited inflammatory cytokine production. IL-13 is a monomeric 17 kDa immunoregulatory cytokine that plays a key role in the pathogenesis of allergy, cancer, and tissue fibrosis. Mature human IL-13 shares approximately 58% amino acid sequence identity with mouse and rat IL-13. It has become evident that IL-13 is a key mediator in the pathogenesis of allergic inflammation, and IL-13 is key proinflammatory cytokines in asthma. The cytokines interleukin IL-13 have pleiotropic effects on a variety of cell types and impact both pathologic changes and tissue remodeling.
    
 
    
Product Properties
    
 
    

    

        

            

                

                
Synonyms
                
                

                
BHR1interleukin-13, IL13, interleukin 13, MGC116786, NC30, P600
                
            
            

                

                
Accession
                
                

                
P20109
                
            
            

                

                
GeneID
                
                

                
16163
                
            
            

                

                
Source
                
                

                
E.coli-derived Mouse IL-13, Pro22-Phe131, with an N-terminal Met.
                
            
            

                

                
Molecular Weight
                
                

                
Approximately 12.3 kDa.
                
            
            

                

                
AA Sequence
                
                

                
MPVPRSVSLP LTLKELIEEL SNITQDQTPL CNGSMVWSVD LAAGGFCVAL DSLTNISNCN AIYRTQRILH GLCNRKAPTT VSSLPDTKIE VAHFITKLLS YTKQLFRHGP F
                
            
            

                

                
Tag
                
                

                
None
                
            
            

                

                
Physical Appearance
                
                

                
Sterile Filtered White lyophilized (freeze-dried) powder.
                
            
            

                

                
Purity
                
                

                
> 97% by SDS-PAGE and HPLC analyses.
                
            
            

                
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