MARK2 polyclonal antibody
产品名称： MARK2 polyclonal antibody
英文名称： MARK2 polyclonal antibody
产品编号： PAB3195
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of MARK2.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human MARK2.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Immunohistochemistry (1:50-100)
Western Blot (1:250-500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Oncogenic kinase signalling.
Blume-Jensen P, Hunter T.Nature. 2001 May 17;411(6835):355-65.
- 2.
- Phosphoinositide 3-kinase signalling pathways.
Cantrell DA.J Cell Sci. 2001 Apr;114(Pt 8):1439-45.
- 3.
- The RET proto-oncogene in human cancers.
Jhiang SM.Oncogene. 2000 Nov 20;19(49):5590-7.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of MARK2 polyclonal antibody (Cat # PAB3195) in HepG2 cell line lysates. MARK2 (arrow) was detected using the purified polyclonal antibody.
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with MARK2 polyclonal antibody (Cat # PAB3195) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. HC = hepatocarcinoma.
- Entrez GeneID:
- 2011
- Protein Accession#:
- Q15524
- Gene Name:
- MARK2
- Gene Alias:
- EMK1,MGC99619,PAR-1,Par1b
- Gene Description:
- MAP/microtubule affinity-regulating kinase 2
- Omim ID:
- 600526
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the Par-1 family of serine/threonine protein kinases. The protein is an important regulator of cell polarity in epithelial and neuronal cells, and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins. The protein localizes to cell membranes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- ELKL motif kinase 1,Ser/Thr protein kinase PAR-1B,protein-serine/threonine kinase,serine/threonine kinase
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