SERTAD1抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
SERTAD1抗体

SERTAD1抗体

商家询价

产品名称： SERTAD1抗体

英文名称： SERTAD1Antibody

产品编号： XY10167-1-

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
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 SERTAD1抗体Applications

In-house applications ELISA, WB     Application not tested? Please see our Guarantee.
Species specificity Human,Mouse,Rat; other species not tested.
Images
Prev1NextView more validation data
  • 10167-1-AP;SH-SY5Y cellsSH-SY5Y cells were subjected to SDS PAGE followed by western blot with 10167-1-AP( SERTAD1 Antibody) at dilution of 1:1000
Positive WB detected in SH-SY5Y cells
Recommended dilution WB : 1:500-1:5000
 SERTAD1抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen SERTAD1 fusion protein ag0180 Full name SERTA domain containing 1
Calculated molecular
weight		 25 kDa Observed molecular 
weight		 25 kDa
GenBank accession 
number		 BC002670 Gene ID (NCBI) 29950
Gene symbol SERTAD1 Synonyms CDK4 binding protein p34SEI1, SEI 1, SEI1, SERTA domain containing 1, SERTAD1, TRIP Br1
Background SERTAD1抗体

SERTA domain containing 1 (SERTAD1, synonyms: SEI1, TRIP-Br1) protein is a cyclin-dependent kinase 4 (cdk4)-binding protein and acts as a growth factor sensor and facilitates the formation and activation of cyclin D-CDK complexes in the face of inhibitory levels of INK4 proteins, therefore, antagonizes the activity of p16(INK4a) tumor suppressor. SERTAD1 also suppresses CREB-mediated transcription and regulates cell cycle progression through sequential effects on the transcriptional activity of E2F-responsive promoters during G(1) and S phases. SERTAD1抗体

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