F13A1 purified MaxPab rabbit polyclonal antibody (D01P)
产品名称： F13A1 purified MaxPab rabbit polyclonal antibody (D01P)
英文名称： F13A1 purified MaxPab rabbit polyclonal antibody (D01P)
产品编号： H00002162-D01P
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against a full-length human F13A1 protein.
- Immunogen:
- F13A1 (AAH27963.1, 1 a.a. ~ 732 a.a) full-length human protein.
- Sequence:
- MSETSRTAFGGRRAVPPNNSNAAEDDLPTVELQGVVPRGVNLQEFLNVTSVHLFKERWDTNKVDHHTDKYENNKLIVRRGQSFYVQIDFSRPYDPRRDLFRVEYVIGRYPQENKGTYIPVPIVSELQSGKWGAKIVMREDRSVRLSIQSSPKCIVGKFRMYVAVWTPYGVLRTSRNPETDTYILFNPWCEDDAVYLDNEKEREEYVLNDIGVIFYGEVNDIKTRSWSYGQFEDGILDTCLYVMDRAQMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSWDNIYAYGVPPSAWTGSVDILLEYRSSENPVRYGQCWVFAGVFNTFLRCLGIPARIVTNYFSAHDNDANLQMDIFLEEDGNVNSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDSTPQENSDGMYRCGPASVQAIKHGHVCFQFDAPFVFAEVNSDLIYITAKKDGTHVVENVDATHIGKLIVTKQIGGDGMMDITDTYKFQEGQEEERLALETALMYGAKKPLNTEGVMKSRSNVDMDFEVENAVLGKDFKLSITFRNNSHNRYTITAYLSANITFYTGVPKAEFKKETFDVTLEPLSFKKEAVLIQAGEYMGQLLEQASLHFFVTARINETRDVLAKQKSTVLTIPEIIIKVRGTQVVGSDMTVIVEFTNPLKETLRNVWVHLDGPGVTRPMKKMFREIRPNSTVQWEEVCRPWVSGHRKLIASMSSDSLRHVYGELDVQIQRRPSM
- Host:
- Rabbit
- Reactivity:
- Human
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- MSDS:
Download
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of F13A1 expression in transfected 293T cell line (H00002162-T01) by F13A1 MaxPab polyclonal antibody.
Lane 1: F13A1 transfected lysate(83.30 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Entrez GeneID:
- 2162
- GeneBank Accession#:
- BC027963.1
- Protein Accession#:
- AAH27963.1
- Gene Name:
- F13A1
- Gene Alias:
- F13A
- Gene Description:
- coagulation factor XIII, A1 polypeptide
- Omim ID:
- 134570
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes the coagulation factor XIII A subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. It also crosslinks alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin. Factor XIII deficiency is classified into two categories: type I deficiency, characterized by the lack of both the A and B subunits; and type II deficiency, characterized by the lack of the A subunit alone. These defects can result in a lifelong bleeding tendency, defective wound healing, and habitual abortion. [provided by RefSeq
- Other Designations:
- FSF, A subunit,TGase,bA525O21.1 (coagulation factor XIII, A1 polypeptide),coagulation factor XIII A1 subunit,coagulation factor XIII, A polypeptide,factor XIIIa,fibrin stabilizing factor, A subunit,fibrinoligase,protein-glutamine gamma-glutamyltransferase
- Interactome
- Gene Pathway
- Related Disease
- Abortion, Habitual
- Abortion, Spontaneous
- Activated Protein C Resistance
- Acute Disease
- Alzheimer Disease
- Alzheimer disease
- Anemia, Sickle Cell
- Anemia, sickle cell
- Aneurysm, Ruptured
- Angina Pectoris
- Antiphospholipid Syndrome
- Arterial Occlusive Diseases
- Arteriosclerosis
- Arthritis, Rheumatoid
- Atherosclerosis
- Atherosclerosis
- Atrial Fibrillation
- beta-Thalassemia
- Blood Coagulation Disorders, Inherited