MAPK1 polyclonal antibody
产品名称: MAPK1 polyclonal antibody
英文名称: MAPK1 polyclonal antibody
产品编号: PAB14843
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of MAPK1.
- Immunogen:
- A synthetic peptide corresponding to amino acids at N-terminus of human MAPK1.
- Sequence:
- FEETARFQPGYRS
- Host:
- Rabbit
- Theoretical MW (kDa):
- 43
- Reactivity:
- Human
- Specificity:
- Identical to the related rat and mouse sequence.
- Form:
- Lyophilized
- Purification:
- Affinity purification
- Storage Buffer:
- Lyophilized from 0.9 mg NaCl, 0.2 mg Na2HPO4 (5 mg BSA, 0.05 mg sodium azide, 0.05 mg Thimerosal)
- Storage Instruction:
- Store at -20°C on dry atmosphere.
After reconstitution with 200 uL of deionized water and concentration will be 500 ug/mL, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide and thimerosal: POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Netrin-1-mediated axon outgrowth requires deleted in colorectal cancer-dependent MAPK activation.
Forcet C, Stein E, Pays L, Corset V, Llambi F, Tessier-Lavigne M, Mehlen P.Nature. 2002 May 23;417(6887):443-7. Epub 2002 May 1.
- 2.
- Requirement of ERK activation for visual cortical plasticity.
Di Cristo G, Berardi N, Cancedda L, Pizzorusso T, Putignano E, Ratto GM, Maffei L.Science. 2001 Jun 22;292(5525):2337-40.
- 3.
- Phosphorylation of the MAP kinase ERK2 promotes its homodimerization and nuclear translocation.
Khokhlatchev AV, Canagarajah B, Wilsbacher J, Robinson M, Atkinson M, Goldsmith E, Cobb MH.Cell. 1998 May 15;93(4):605-15.
- Application Image
- Western Blot
- Entrez GeneID:
- 5594
- Gene Name:
- MAPK1
- Gene Alias:
- ERK,ERK2,ERT1,MAPK2,P42MAPK,PRKM1,PRKM2,p38,p40,p41,p41mapk
- Gene Description:
- mitogen-activated protein kinase 1
- Omim ID:
- 176948
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq
- Other Designations:
- OTTHUMP00000174492,extracellular signal-regulated kinase 2,extracellular signal-regulated kinase-2,mitogen-activated protein kinase 2,protein tyrosine kinase ERK2
- Gene Pathway
- Acute myeloid leukemia
- Adherens junction
- Alzheimer's disease
- Axon guidance
- B cell receptor signaling pathway
- Bladder cancer
- Chemokine signaling pathway
- Chronic myeloid leukemia
- Colorectal cancer
- Dorso-ventral axis formation
- Endometrial cancer
- ErbB signaling pathway
- Fc epsilon RI signaling pathway
- Fc gamma R-mediated phagocytosis
- Focal adhesion
- Gap junction
- Glioma
- GnRH signaling pathway
- Insulin signaling pathway
- Long-term depression
- Long-term potentiation
- MAPK signaling pathway
- Melanogenesis
- Melanoma
- mTOR signaling pathway
- Natural killer cell mediated cytotoxicity
- Neurotrophin signaling pathway
- Non-small cell lung cancer
- Pancreatic cancer
- Pathways in cancer
- Prion diseases
- Prostate cancer
- Regulation of actin cytoskeleton
- Renal cell carcinoma
- T cell receptor signaling pathway
- TGF-beta signaling pathway
- Thyroid cancer
- Toll-like receptor signaling pathway
- Type II diabetes mellitus
- Vascular smooth muscle contraction
- VEGF signaling pathway