ENPP3 monoclonal antibody, clone NP4D6
产品名称： ENPP3 monoclonal antibody, clone NP4D6
英文名称： ENPP3 monoclonal antibody, clone NP4D6
产品编号： MAB6497
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against native ENPP3.
- Immunogen:
- Native purified from HEK293 cells transfected with human ENPP3.
- Host:
- Mouse
- Reactivity:
- Human
- Specificity:
- This antibody NP4D6 reacts with CD203C, a transmembrane ectoenzyme expressed on basophils and mast cells, and overexpressed upon their activation.
- Form:
- Liquid
- Concentration:
- 1 mg/mL
- Isotype:
- IgG1
- Storage Buffer:
- In PBS, pH 7.4 (15 mM sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Hymenoptera-venom-induced upregulation of the basophil activation marker ecto-nucleotide pyrophosphatase/phosphodiesterase 3 in sensitized individuals.
Platz IJ, Binder M, Marxer A, Lischka G, Valent P, Buhring HJ.Int Arch Allergy Immunol. 2001 Dec;126(4):335-42.
- 2.
- The basophil activation marker defined by antibody 97A6 is identical to the ectonucleotide pyrophosphatase/phosphodiesterase 3.
Buhring HJ, Seiffert M, Giesert C, Marxer A, Kanz L, Valent P, Sano K.Blood. 2001 May 15;97(10):3303-5.
- 3.
- The monoclonal antibody 97A6 defines a novel surface antigen expressed on human basophils and their multipotent and unipotent progenitors.
Buhring HJ, Simmons PJ, Pudney M, Muller R, Jarrossay D, van Agthoven A, Willheim M, Brugger W, Valent P, Kanz L.Blood. 1999 Oct 1;94(7):2343-56.
- Entrez GeneID:
- 5169
- Gene Name:
- ENPP3
- Gene Alias:
- B10,CD203c,NPP3,PD-IBETA,PDNP3
- Gene Description:
- ectonucleotide pyrophosphatase/phosphodiesterase 3
- Omim ID:
- 602182
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene belongs to a series of ectoenzymes that are involved in hydrolysis of extracellular nucleotides. These ectoenzymes possess ATPase and ATP pyrophosphatase activities and are type II transmembrane proteins. Expression of the related rat mRNA has been found in a subset of immature glial cells and in the alimentary tract. The corresponding rat protein has been detected in the pancreas, small intestine, colon, and liver. The human mRNA is expressed in glioma cells, prostate, and uterus. Expression of the human protein has been detected in uterus, basophils, and mast cells. [provided by RefSeq
- Other Designations:
- OTTHUMP00000040272,dJ1005H11.3 (phosphodiesterase I/nucleotide pyrophosphatase 3),dJ914N13.3 (phosphodiesterase I/nucleotide pyrophosphatase 3),gp130RB13-6,phosphodiesterase I/nucleotide pyrophosphatase 3,phosphodiesterase-I beta
- Related Disease