TNFSF15 (Human) Recombinant Protein
产品名称： TNFSF15 (Human) Recombinant Protein
英文名称： TNFSF15 (Human) Recombinant Protein
产品编号： H00009966-H01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- Specification
- Product Description:
- Purified TNFSF15 (AAH74941.1, 72 a.a. - 251 a.a.) human recombinant protein with His-Flag-StrepII tag at N-terminus expressed in human cells.
- Transfected Cell Line:
- Human HEK293T cells
- Sequence:
- LKGQEFAPSHQQVYAPLRADGDKPRAHLTVVRQTPTQHFKNQFPALHWEHELGLAFTKNRMNYTNKFLLIPESGDYFIYSQVTFRGMTSECSEIRQAGRPNKPDSITVVITKVTDSYPEPTQLLMGTKSVCEVGSNWFQPIYLGAMFSLQEGDKLMVNVSDISLVDYTKEDKTFFGAFLL
- Host:
- Human
- Theoretical MW (kDa):
- 25.08
- Form:
- Liquid
- Preparation Method:
- Transfection of pSuper-TNFSF15 plasmid into HEK293T cell, and the expressed protein was purified by Strep-Tactin affinity column.
- Purification:
- Strep-Tactin affinity columns
- Concentration:
- > 10 ug/ml
- Activity:
- Not Tested
- Storage Buffer:
- 100 mM Tris-HCl pH 8.0, 150 mM NaCl, 1 mM EDTA, and 5 mM desthiobiotin.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- SDS-PAGE and Western Blot
SDS-PAGE Gel
Western Blot
- Application Image
- Western Blot
- Enzyme-linked Immunoabsorbent Assay
- SDS-PAGE
- Protein Interaction
- Entrez GeneID:
- 9966
- GeneBank Accession#:
- BC074941.2
- Protein Accession#:
- AAH74941.1
- Gene Name:
- TNFSF15
- Gene Alias:
- MGC129934,MGC129935,TL1,TL1A,VEGI,VEGI192A
- Gene Description:
- tumor necrosis factor (ligand) superfamily, member 15
- Omim ID:
- 604052
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. An additional isoform encoded by an alternatively spliced transcript variant has been reported but the sequence of this transcript has not been determined. [provided by RefSeq
- Other Designations:
- OTTHUMP00000022739,TNF ligand-related molecule 1,TNF superfamily ligand TL1A,vascular endothelial cell growth inhibitor,vascular endothelial growth inhibitor-192A
- Gene Pathway